{"id":31967,"date":"2025-09-22T12:52:59","date_gmt":"2025-09-22T10:52:59","guid":{"rendered":"https:\/\/uni-freiburg.de\/en\/?p=31967"},"modified":"2025-09-22T12:53:01","modified_gmt":"2025-09-22T10:53:01","slug":"growth-switch-for-plant-adaptability-discovered","status":"publish","type":"post","link":"https:\/\/uni-freiburg.de\/en\/growth-switch-for-plant-adaptability-discovered\/","title":{"rendered":"Growth switch for plant adaptability discovered"},"content":{"rendered":"\n<div class=\"[&amp;amp;&amp;gt;*]:bl-relative last:[&amp;amp;&amp;gt;*.bl-absolute]:bl-absolute\n\t\t\t[&amp;amp;&amp;gt;*]:bl-z-20 last:[&amp;amp;&amp;gt;*]:bl-z-10 bl-relative bl-overflow-x-clip\n\t\t\t[.wp-block-ufr-section_&amp;amp;]:bl-overflow-x-visible\n\t\t\tbl-bg-identity-lightblue bl-text-identity-black dark:bl-bg-identity-lightblue dark:bl-text-identity-black bl-py-[24px] alignfull wp-block-ufr-section has-global-padding is-layout-constrained wp-block-ufr-section-is-layout-constrained\">\n\n\t\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:15%\"><\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:70%\">\n<p><em>Freiburg, 22.09.2025<\/em><\/p>\n\n\n\n<p><strong>Researchers in Freiburg have discovered a mechanism by which plant hormones are specifically regulated to adapt growth to environmental conditions \u2013 controlled by the so-called ERAD machinery. The study has been published in the journal <em>Science Advances<\/em>. The findings could help make crops more resilient and agriculture more sustainable in the future.<\/strong><\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:15%\"><\/div>\n<\/div>\n\n\t<\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"773\" src=\"https:\/\/uni-freiburg.de\/en\/wp-content\/uploads\/sites\/61\/Arabidopsis-Pflanze-in-Laborbedingung_bearbeitet2-1024x773.jpg\" alt=\"Arabidopsis plant in laboratory conditions. \" class=\"wp-image-31969\" srcset=\"https:\/\/uni-freiburg.de\/en\/wp-content\/uploads\/sites\/61\/Arabidopsis-Pflanze-in-Laborbedingung_bearbeitet2-1024x773.jpg 1024w, https:\/\/uni-freiburg.de\/en\/wp-content\/uploads\/sites\/61\/Arabidopsis-Pflanze-in-Laborbedingung_bearbeitet2-300x226.jpg 300w, https:\/\/uni-freiburg.de\/en\/wp-content\/uploads\/sites\/61\/Arabidopsis-Pflanze-in-Laborbedingung_bearbeitet2-768x579.jpg 768w, https:\/\/uni-freiburg.de\/en\/wp-content\/uploads\/sites\/61\/Arabidopsis-Pflanze-in-Laborbedingung_bearbeitet2-1536x1159.jpg 1536w, https:\/\/uni-freiburg.de\/en\/wp-content\/uploads\/sites\/61\/Arabidopsis-Pflanze-in-Laborbedingung_bearbeitet2-2048x1545.jpg 2048w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><figcaption class=\"wp-element-caption\"><em>Arabidopsis plant in laboratory conditions. Photo: J\u00fcrgen Kleine-Vehn<\/em><\/figcaption><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-top is-layout-flow wp-block-column-is-layout-flow\">\n<p>How does a plant manage to quickly adapt its growth to changing environmental conditions? A research team at the University of Freiburg led by plant physiologist Prof. Dr. <strong>J\u00fcrgen Kleine-Vehn<\/strong> has discovered a previously unknown mechanism for this: a cellular degradation machinery acts in the background like a switch that decides whether the plant hormone auxin is available or not. This mechanism enables the plant to respond to the environment and dynamically regulate its growth, whether it be root growth in the soil or shoot curvature towards the light. The results have been published in the journal <em>Science Advances<\/em>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong><strong><strong>PILS proteins as gatekeepers<\/strong><\/strong><\/strong><\/h2>\n\n\n\n<p>At the heart of the newly discovered control mechanism are the so-called PILS proteins. They act like gatekeepers: sometimes they retain auxin inside the cell, sometimes they release it for growth. Which decision is made depends on how many of these proteins are present. The Freiburg researchers have now been able to show that a cellular degradation machinery, known as ERAD machinery, regulates the number of PILS proteins as needed. If auxin is required due to changes in the environment, the gatekeepers are degraded and the plant changes its growth mode. Under stable conditions, however, the proteins remain in place and inhibit the hormone response.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div style=\"height:25px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:66.66%\"><div class=\"bl-@container\/quote\">\n\t<div class=\"bl-flex bl-flex-col @[542px]\/quote:bl-flex-row xl:@[542px]\/quote:bl-flex-col xl:@[810px]\/quote:bl-flex-row bl-mb-[56px] md:bl-mb-[70px] bl-gap-[15px] md:bl-gap-[20px] @[542px]:bl-gap-4 md:@[542px]:bl-gap-4\">\n\t\t\t\t<div class=\"\n\t\t\tbl-flex bl-flex-col bl-items-center\n\t\t\tmd:@[542px]\/quote:bl-min-w-[220px] xl:@[542px]\/quote:bl-min-w-[295px] 2xl:@[542px]\/quote:bl-min-w-[460px]\n\t\t\">\n\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/uni-freiburg.de\/en\/wp-content\/uploads\/sites\/61\/Portraitfoto-Kleine-Vehn_1000px.jpg\" alt=\"\"\n\t\t\tclass=\"bl-rounded-full bl-w-[170px] !bl-h-[170px] md:bl-w-[119px] md:!bl-h-[119px] xl:bl-w-[159px] xl:!bl-h-[159px] 2xl:bl-w-[250px] 2xl:!bl-h-[250px] bl-object-cover\">\n\t\t\t\t\t<\/div>\n\t\t<div class=\"bl-flex-col bl-flex-1\">\n\t\t\t\t\t\t<p class=\"bl-text-[1.125rem] bl-leading-[1.5625rem] md:bl-text-[1.25rem] xl:bl-text-[1.5625rem] xl:bl-leading-[2.1875rem] bl-font-medium bl-mt-0 !bl-text-identity-black [&amp;_a]:!bl-text-identity-black hover:[&amp;_a]:!bl-text-identity-blue-60 active:[&amp;_a]:!bl-text-identity-blue dark:!bl-text-pure-white dark:[&amp;_a]:!bl-text-pure-white dark:hover:[&amp;_a]:!bl-text-identity-yellow-60 dark:active:[&amp;_a]:!bl-text-identity-yellow\">\n\t\t\t\t\u201cYou can think of this mechanism as a molecular switch. The plant decides whether auxin is effective or not, which thus flexibly adapts its growth to the environment.\u201d \t\t\t<\/p>\n\t\t\t\t\t\t\t\t\t<div class=\"bl-w-[59px] bl-h-[1px] bl-my-[20px] md:bl-my-[25px] xl:bl-my-[30px] bl-bg-identity-black dark:bl-bg-pure-white\"><\/div>\n\t\t\t\t\t\t\t\t\t<h3 class=\"bl-text-[1rem] bl-leading-[1.375rem] md:bl-text-[1.125rem] xl:bl-text-[1.375rem] xl:bl-leading-[2.0625rem] bl-font-medium bl-mb-0 !bl-text-identity-black [&amp;_a]:!bl-text-identity-black hover:[&amp;_a]:!bl-text-identity-blue-60 active:[&amp;_a]:!bl-text-identity-blue dark:!bl-text-pure-white dark:[&amp;_a]:!bl-text-pure-white dark:hover:[&amp;_a]:!bl-text-identity-yellow-60 dark:active:[&amp;_a]:!bl-text-identity-yellow\">\n\t\t\t\tProf. Dr. J\u00fcrgen Kleine-Vehn\t\t\t<\/h3>\n\t\t\t\t\t\t<h4 class=\"bl-text-[1rem] bl-leading-[1.375rem] md:bl-text-[1.125rem] md:bl-leading-[1.5625rem] xl:bl-text-[1.375rem] xl:bl-leading-[2.0625rem] bl-font-book bl-my-0 bl-mb-[5px] xl:bl-mb-[10px] !bl-text-identity-black [&amp;_a]:!bl-text-identity-black hover:[&amp;_a]:!bl-text-identity-blue-60 active:[&amp;_a]:!bl-text-identity-blue dark:!bl-text-pure-white dark:[&amp;_a]:!bl-text-pure-white dark:hover:[&amp;_a]:!bl-text-identity-yellow-60 dark:active:[&amp;_a]:!bl-text-identity-yellow\">\n\t\t\t\tProfessor of Molecular Plant Physiology at the Faculty of Biology at the University of Freiburg and member and spokesperson for the CIBSS Cluster of Excellence\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><strong><strong>Possible key to sustainable agriculture in the future<\/strong><\/strong><\/h2>\n\n\n\n<p>\u201cYou can think of this mechanism as a molecular switch,\u201d says study leader Kleine-Vehn. \u201cThe plant decides whether auxin is effective or not, which thus flexibly adapts its growth to the environment.\u201d The discovery opens up a new perspective on the fine control of plant development. It shows how closely internal control mechanisms and external signals are interlinked.<\/p>\n\n\n\n<p><strong>Seinab Noura<\/strong>, a biologist at the University of Freiburg and first author of the study, also emphasises the significance of the findings: \u201cIf we make targeted use of such mechanisms, crops could become more resistant to stress.\u201d In the long term, this knowledge could also help to make plants more robust against climate change, a key factor for sustainable agriculture in the future.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:33.33%\"><\/div>\n<\/div>\n\n\n\n<div style=\"height:25px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:66.66%\">\n<div class=\"[&amp;amp;&amp;gt;*]:bl-relative last:[&amp;amp;&amp;gt;*.bl-absolute]:bl-absolute\n\t\t\t[&amp;amp;&amp;gt;*]:bl-z-20 last:[&amp;amp;&amp;gt;*]:bl-z-10 bl-relative bl-overflow-x-clip\n\t\t\t[.wp-block-ufr-section_&amp;amp;]:bl-overflow-x-visible\n\t\t\tbl-bg-identity-lightblue bl-text-identity-black dark:bl-bg-identity-lightblue dark:bl-text-identity-black bl-py-[24px]  align wp-block-ufr-section has-global-padding is-layout-constrained wp-block-ufr-section-is-layout-constrained\">\n\n\t\n\n<h3 class=\"wp-block-heading\"><strong><strong>Further Information<\/strong><\/strong><\/h3>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:66.66%\">\n<ul class=\"wp-block-list\">\n<li><strong>Original publication<\/strong>: Seinab Noura, Jonathan Ferreira Da Silva Santos, Elena Feraru, Sebastian N.W. Hoernstein, Mugurel I. Feraru, Laura Montero-Morales, Ann-Kathrin R\u00f6\u00dfling, David Scheuring, Richard Strasser, Pitter F. Huesgen, Sascha Waidmann, J\u00fcrgen Kleine-Vehn: ERAD machinery controls the conditional turnover of PIN-LIKES in plants. In: <em>Science Advances<\/em>. DOI: https:\/\/doi.org\/10.1126\/sciadv.adx5027<\/li>\n\n\n\n<li>Prof. Dr. J\u00fcrgen Kleine-Vehn is Professor of Molecular Plant Physiology at the Faculty of Biology at the University of Freiburg. Since 2024, he has also been spokesperson for the Cluster of Excellence CIBSS \u2013 Centre for Integrative Biological Signalling Studies. His research focuses on the molecular cell biology of plants.<\/li>\n\n\n\n<li>The work was carried out as part of the CIBSS \u2013 Centre for Integrative Biological Signalling Studies cluster of excellence at the University of Freiburg and was funded by the German Research Foundation (DFG).<\/li>\n<\/ul>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:33.33%\">\n<div class=\"is-layout-flex wp-block-ufr-buttons-is-layout-flex\">\n\t\n\n<div class=\"wp-block-ufr-button\"> \n\t<a href=\"https:\/\/doi.org\/10.1126\/sciadv.adx5027\"\n\t\t\t\taria-label=\"\"\n\t\tclass=\"\n\t\tbl-text-[1.125rem] bl-leading-[1.5625rem] bl-px-[26px] bl-py-[7px] bl-border-[2px] bl-gap-[8px] !bl-decoration-2 !bl-underline-offset-[5px] focus-visible:bl-outline-offset-[6px]\t\tbl-no-underline hover:bl-underline bl-font-medium\n\t\t\n\t\tfocus-visible:bl-outline-dotted focus-visible:bl-outline-2 bl-border-identity-black bl-text-identity-black\n\t   hover:bl-bg-identity-blue-80 hover:bl-border-identity-blue-80 hover:bl-text-pure-white\n\t   active:bl-bg-identity-blue active:bl-text-pure-white active:bl-border-identity-blue\n\t   !bl-outline-identity-black dark:!bl-border-identity-black dark:bl-text-identity-black\n\t\tdark:hover:bl-bg-identity-blue-80 dark:hover:!bl-border-identity-blue-80 dark:hover:bl-text-pure-white\n\t\tdark:active:bl-bg-identity-blue dark:active:bl-text-pure-white dark:active:!bl-border-identity-blue\n\t\tdark:!bl-outline-identity-black\t\tbl-inline-flex bl-flex-row bl-items-center motion-safe:bl-transition-colors\n\t\tmotion-safe:bl-duration-[400ms] justify-center bl-hyphens-auto\n\t\t\">\n\t\t\t\t<span class=\"bl-inline-block\">\n\t\t\tOriginal Publication\t\t<\/span>\n\t<\/a>\n<\/div>\n\n<\/div>\n\n<\/div>\n<\/div>\n\n\t<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:33.33%\"><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<div class=\"bl-@container\/teaser-service\n\tbl-bg-identity-blue bl-text-pure-white dark:bl-bg-identity-blue dark:bl-text-pure-white\n\tbl-self-stretch\n\tbl-px-[25px] bl-py-[20px]\n\tmd:!bl-px-[45px] md:!bl-py-[40px]\n\txl:!bl-px-[55px] xl:!bl-py-[50px]\n\tbl-min-w-full md:bl-min-w-[670px] xl:bl-min-w-[320px] wp-block-ufr-teaser-service wp-container-content-9cfa9a5a\" >\n\n\t<div\n\t\taria-hidden=\"true\"\n\t\tclass=\"bl-float-right rtl:bl-float-left\n\t\t\tbl-bg-pure-white\n\t\t\t-bl-mt-[20px] md:-bl-mt-[40px] xl:-bl-mt-[50px]\n\t\t\t-bl-mr-[5px] md:-bl-mr-[25px] xl:-bl-mr-[20px]\n\t\t\tbl-w-[35px] bl-h-[40px] @sm\/teaser-service:md:!-bl-mr-[20px]\n\t\t\t@md\/teaser-service:xl:!-bl-mr-[20px] @md\/teaser-service:xl:!-bl-mt-[50px]\n\t\t\t@md\/teaser-service:md:!-bl-mr-[25px] 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dark:bl-text-inherit\n\t\tbl-text-[1.25rem] bl-leading-[1.75rem]\n\t\tmd:bl-text-[1.5rem] md:bl-leading-[2.25rem]\n\t\txl:bl-text-[2.3125rem] xl:bl-leading-[3.125rem] [overflow-wrap:anywhere]\">\n\t\tContact\t<\/p>\n\t<p class=\"font-medium bl-mt-[10px] bl-mb-0\n\t\tbl-text-[1rem] bl-leading-[1.375rem]\n\t\tmd:bl-text-[1.125rem] md:bl-leading-[1.375rem]\n\t\txl:bl-text-[1.375rem] xl:bl-leading-[2.0625rem] [overflow-wrap:anywhere]\">\n\t\tUniversity and Science Communications\t<\/p>\n\t<p class=\"font-book bl-mt-[20px] xl:bl-mt-[30px] bl-mb-0\n\t\tbl-text-[1rem] bl-leading-[1.375rem]\n\t\tmd:bl-text-[1.125rem] md:bl-leading-[1.625rem]\n\t\txl:bl-text-[1.375rem] xl:bl-leading-[2.0625rem]\">\n\t\tUniversity of Freiburg<br>Tel.:&nbsp;<a href=\"tel:+497612034302\">+49 761 203 4302<\/a><br>E-Mail:&nbsp;<a href=\"mailto:kommunikation@zv.uni-freiburg.de\">kommunikation@zv.uni-freiburg.de<\/a>\t<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:30%\"><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>How does a plant manage to quickly adapt its growth to changing environmental conditions? A research team at the University of Freiburg led by plant physiologist Prof. Dr. J\u00fcrgen Kleine-Vehn has discovered a previously unknown mechanism for this: a cellular degradation machinery acts in the background like a switch that decides whether the plant hormone<\/p>\n","protected":false},"author":77,"featured_media":31969,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_trash_the_other_posts":false,"editor_notices":[],"_show_in_pageentry_slider":true,"_pageentry_slider_title":"Growth switch for plant adaptability discovered","footnotes":""},"categories":[29,25],"tags":[],"class_list":["post-31967","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cibbs","category-research"],"featured_image_url":"https:\/\/uni-freiburg.de\/en\/wp-content\/uploads\/sites\/61\/Arabidopsis-Pflanze-in-Laborbedingung_bearbeitet2.jpg","featured_image_alt":"Arabidopsis plant in laboratory conditions.","_links":{"self":[{"href":"https:\/\/uni-freiburg.de\/en\/wp-json\/wp\/v2\/posts\/31967","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/uni-freiburg.de\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/uni-freiburg.de\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/uni-freiburg.de\/en\/wp-json\/wp\/v2\/users\/77"}],"replies":[{"embeddable":true,"href":"https:\/\/uni-freiburg.de\/en\/wp-json\/wp\/v2\/comments?post=31967"}],"version-history":[{"count":2,"href":"https:\/\/uni-freiburg.de\/en\/wp-json\/wp\/v2\/posts\/31967\/revisions"}],"predecessor-version":[{"id":31971,"href":"https:\/\/uni-freiburg.de\/en\/wp-json\/wp\/v2\/posts\/31967\/revisions\/31971"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/uni-freiburg.de\/en\/wp-json\/wp\/v2\/media\/31969"}],"wp:attachment":[{"href":"https:\/\/uni-freiburg.de\/en\/wp-json\/wp\/v2\/media?parent=31967"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/uni-freiburg.de\/en\/wp-json\/wp\/v2\/categories?post=31967"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/uni-freiburg.de\/en\/wp-json\/wp\/v2\/tags?post=31967"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}