PhD Student (m/f/d) 80 % Optimization of Carbon Electrode Interfaces for Reagent-Free Electrochemical Detection at the Point of Need In the Electrochemical Biosensors Group

We are seeking a highly motivated PhD student to contribute to the development of robust carbon electrode interfaces for electrochemical multi-analyte detection in human body fluids. The project combines fundamental surface engineering with translational biosensor development in a highly interdisciplinary research environment.

You will work on the optimization and scalable implementation of biofunctionalization strategies to enhance the robustness, and analytical performance of electrochemical biosensors. A key focus will be the reduction of biofouling and the improvement of signal quality in complex biological matrices, with the aim of enabling reliable sample-to-answer solutions for future diagnostic applications.

Your tasks

• Develop advanced electrode functionalization strategies, including tailored anti-biofouling surface modifications.
• Establish scalable DNA-based biofunctionalization of electrodes.
• Investigate multiplexing strategies for molecular isothermal and aptamer-based detection.
• Integrate molecular assays into sample-to-answer cartridges.
• Analyze and process data to reduce interference from complex biological matrices.

Your profile

• Degree (Master of Science or equivalent) in chemistry, biochemistry, biophysics or related discipline.
• Knowledge of electrochemical methods such as cyclic voltammetry and SWV is an advantage.
• Experience with surface chemistry on gold or carbon, and simple organic syntheses, is an asset.
• Structured, independent, and meticulous working style with strong planning and documentation skills.
• Curiosity to learn new methods and contribute to a multidisciplinary team.
• Entrepreneurial mindset and interest in spin-off formation are an asset.

We offer

• An attractive position in a modern, well-equipped, and industry-oriented research institute, offering exciting insights into medical device research and development.
• Close scientific supervision and comprehensive onboarding into the research topic.
• A fixed-term position for 2 years, with the possibility of extension.