Prof. Dr. Anne-Kathrin Claßen

Focus of research

• collective cell behaviors in epithelial morphogenesis
• tissue regeneration and tumor growth
• cell-cell competition and tissue-intrinsic tumor suppression

CV

• 2022 Heisenberg Professor, University of Freiburg, Germany
• 2017–2021 Boehringer Ingelheim Stiftung Plus3 Group Leader, University of Freiburg, Germany
• 2017 Interim Professor Cell Biology, University of Freiburg, Germany
• 2011–2017 Emmy Noether Group Leader, LMU Munich, Germany
• 2006–2010 Postdoc, UC Berkeley, USA
• 2006 PhD in Biology, MPI-CBG and TU Dresden, Germany
• 2002 MSc in Biomolecular Sciences, University of Amsterdam, Netherlands
• 2000 BSc in Cell Biology, University of Manchester, UK

Selected publications

• A mismatch in the expression of cell surface molecules induces tissue-intrinsic defense against aberrant cells. Fischer F, Ernst L, Frey A, Holstein K, Prasad D, Weichselberger V, Balaji R, Classen AK (2024). Current Biology. doi.org/10.1016/j.cub.2024.01.053
• Mutual repression between JNK/AP-1 and JAK/STAT stratifies senescent and proliferative cell behaviors during tissue regeneration. Jaiswal J, Egert J, Engesser R, Peyrotón AA, Nogay L, Weichselberger V, Crucianelli C, Grass I, Kreutz C, Timmer J and Classen AK (2023). PLOS Biology. doi.org/10.1371/journal.pbio.3001665.
• Eya-controlled affinity between cell lineages drives tissue self-organization during Drosophila oogenesis. Weichselberger V, Dondl P, Classen AK (2022). Nature Communications. doi.org/10.1038/s41467-022-33845-1
• JNK-dependent cell cycle stalling in G2 promotes survival and senescence-like phenotypes in tissue stress. Cosolo A, Jaiswal J, Csordás G, Grass I, Uhlirova M, Classen AK (2019). Elife. doi: 10.7554/eLife.41036
• Interface contractility between differently fated cells drives cell elimination and cyst formation. Bielmeier C, Alt S, Weichselberger V, Fortezza M, Harz H, Jülicher F, Salbreux G, Classen AK (2016). Current Biology. doi: 10.1016/j.cub.2015.12.063.