Prof. Dr. Anne-Kathrin Claßen
Focus of research
- collective cell behaviors in epithelial morphogenesis
- tissue regeneration and tumor growth
- cell-cell competition and tissue-intrinsic tumor suppression
CV
- 2022 Heisenberg Professor, University of Freiburg, Germany
- 2017–2021 Boehringer Ingelheim Stiftung Plus3 Group Leader, University of Freiburg, Germany
- 2017 Interim Professor Cell Biology, University of Freiburg, Germany
- 2011–2017 Emmy Noether Group Leader, LMU Munich, Germany
- 2006–2010 Postdoc, UC Berkeley, USA
- 2006 PhD in Biology, MPI-CBG and TU Dresden, Germany
- 2002 MSc in Biomolecular Sciences, University of Amsterdam, Netherlands
- 2000 BSc in Cell Biology, University of Manchester, UK
Recent publications
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Vijayakumar Maya, A., Neuhaus, L., Nogay, L., Singh, A., Heckmann, L., Grass, I., Buescher, J. M., Kierdorf, K., & Classen, A.-K. (2025). A JAK/STAT-Pdk1-S6K axis bypasses systemic growth restrictions to promote regeneration. Nature Communications, 16, 10944. https://doi.org/10.1038/s41467-025-66995-z
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Fischer, F., Ernst, L., Frey, A.-V., Holstein, K., Prasad, D., Weichselberger, V. J. B., Balaji, R., & Classen, A.-K. (2024). A mismatch in the expression of cell surface molecules induces tissue-intrinsic defense against aberrant cells. Current Biology, 34(5), 980–996.e6. https://doi.org/10.1016/j.cub.2024.01.053
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Hersperger, F., Meyring, T., Weber, P., Chhatbar, C., Monaco, G., Dionne, M. S., Paeschke, K., Prinz, M., Groß, O., Classen, A.-K., & Kierdorf, K. (2024). DNA damage signaling in Drosophila macrophages modulates systemic cytokine levels in response to oxidative stress. eLife, 12, RP86700. https://doi.org/10.7554/elife.86700
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Jaiswal, J., Egert, J., Engesser, R., Peyrotón, A. A., Nogay, L., Weichselberger, V. J. B., Crucianelli, C., Grass, I., Kreutz, C., Timmer, J., & Classen, A.-K. (2023). Mutual repression between JNK/AP-1 and JAK/STAT stratifies senescent and proliferative cell behaviors during tissue regeneration. PLOS Biology, 21(5), e3001665. https://doi.org/10.1371/journal.pbio.3001665
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Floc’hlay, S., Balaji, R., Stanković, D., Christiaens, V. M., Bravo González-Blas, C., De Winter, S., Hulselmans, G. J., Waegeneer, M. de, Quan, X., Koldere, D., Atkins, M., Halder, G., Uhlirova, M., Classen, A.-K., & Aerts, S. (2023). Shared enhancer gene regulatory networks between wound and oncogenic programs. eLife, 12, e81173. https://doi.org/10.7554/elife.81173