Dr. Thomas Heimbucher

Focus of research

• Metabolic regulation of organismal health and longevity
• Metabolic signaling in aging and stress response
• Transcriptional control of lipid metabolism in neuroprotection and survival

CV

• Research group leader, University of Freiburg (Germany, since 2019)
• Associate Scholar, Princeton University (New Jersey, USA, 2016-2018)
• Postdoc, Salk Institute for Biological Studies (California, USA, 2008-2015)
• PhD in Molecular Biology, University of Vienna (Austria)

Selected publications

• Wu G., Baumeister R., Heimbucher T. Molecular Mechanisms of Lipid-Based Metabolic Adaptation Strategies in Response to Cold. Cells. 2023 May 10;12(10): 1353.
• Baumeister R., Murphy C.T., and Heimbucher T. Metabolic adaptation to hypoxia: do worms and cancer cells share common metabolic responses to hypoxic stress? Cell Death Differ, 2021. 28(4): 1434-1436.
• Heimbucher T.*, Hog J., Gupta P., Murphy C.T.* PQM-1 controls hypoxic survival via regulation of lipid metabolism. Nat Commun, 2020. 11(1): 4627. *corresponding author
• Heimbucher T., and Murphy CT. PBX/MEIS transcription factors find the balance between reproduction and somatic resilience. Dev. Cell. 2019 Apr 22;49(2): 157-158.
• Heimbucher T., Liu Z., Bossard C., McCloskey R., Carrano A., Riedel CG., Tanasa B., Klammt C., Fonslo BR., Riera C., Kemphues K., Lillemeier BF., Yates JR., O’Shea C., Hunter T., and Dillin A. The Deubiquitylase MATH-33 Controls DAF-16 Stability and Function in Metabolism and Longevity. Cell Metab. 2015 Jul 7; 22(1): 151-63