Prof. Dr. Wolfgang R. Hess
Focus of research
- RNA biology using experimental and biocomputational approaches
- Microbial systems biology
- Biology of native CRISPR systems and their application
CV
- 2017–2019 Senior fellow of the Freiburg Institute for Advanced Studies (FRIAS) and the University of Strasbourg Institute for Advanced Study (USIAS) in France
- 2012 William Evans Guest Professorship, University of Otago, Dunedin, New Zealand
- since 2010 Elected Director of the Institute for Biology 3, University of Freiburg, Germany
- since 2010 Head of the Examination Committee, Faculty of Biology, University of Freiburg, Germany
- since 2008 Full Professor (W3) for Genetics, Faculty of Biology, University of Freiburg, Germany
- 2004–2007 Professor for Experimental Bioinformatics (C3), Faculty of Biology, University of Freiburg, Germany
- 2003–2004 Funding Director, Ocean Genome Legacy Foundation, affiliated with New England Biolabs, Beverly, U.S.
- 1999–2002 Associate Professor Genetics (C2), Faculty of Natural Sciences, Humboldt-University Berlin, Germany
- 1999 Habilitation (Genetics), Faculty of Natural Sciences, Humboldt-University Berlin, Germany
- 1994–1999 Assistant Professor Genetics (C1), Faculty of Natural Sciences, Humboldt-University Berlin, Germany
- 1993–1994 Postdoctoral Research Fellow, Observatoire Océanologique de Roscoff, CNRS, France
- 1990 PhD in Genetics (Dr. rer. nat.), Faculty of Natural Sciences, Humboldt-University Berlin, Germany
Selected publications
- Brenes-Álvarez M., Ropp H.R., Papagiannidis D., Potel C., Stein F., Scholz I., Steglich C., Savitski M., Vioque A., Muro-Pastor A.M., Hess W.R. (2025) R-DeeP/TripepSVM identifies the RNA-binding OB-fold-like protein PatR as regulator of heterocyst patterning. Nucleic Acids Resarch 53, gkae1247.
- Kraus A., Spät P., Timm S., Wilson A., Schumann R., Hagemann M., Maček B., Hess W.R. (2024) Protein NirP1 regulates nitrite reductase and nitrite excretion in cyanobacteria. Nature Communications 15, 1911.
- Ziemann M., Reimann V., Liang Y., Shi Y., Ma H., Xie Y., Li H., Zhu T., Lu X., Hess W.R. (2023) CvkR is a MerR-type transcriptional repressor of class 2 type V-K CRISPR-associated transposase systems. Nature Communications 14, 924.
- Song K., Baumgartner D., Hagemann M., Muro-Pastor A.M., Maaß S., Becher D., Hess W.R. (2022) AtpΘ is an inhibitor of F0F1 ATP synthase to arrest ATP hydrolysis during low-energy conditions in cyanobacteria. Current Biology 32, 1–14.
- Behler J., Sharma K., Reimann V., Wilde A., Urlaub H., Hess W.R. (2018) The host-encoded RNase E endonuclease as the crRNA maturation enzyme in a CRISPR-Cas subtype III-Bv system. Nature Microbiol. 3, 367–377.