PD Dr. Daria Onichtchouk
Focus of research
- The mechanisms of zygotic genome activation.
- Cell specification in early zebrafish development
- Role of pioneer transcription factors in early embryonic development
CV
- Since 2013 Group leader, Department of Developmental Biology, Faculty of Biology, University of Freiburg
- 2015 Habilitation, Venia Legendi (teaching authorization) for the subject Developmental Biology of Animals, Faculty of Biology, University of Freiburg
- 2006–2012 Academic Councillor, Department of Developmental Biology (Prof. Driever), Faculty of Biology, University of Freiburg
- 2001–2006 Senior Scientist, DeveloGen AG, Göttingen
- 1999–2001 Postdoctoral researcher at the MPI for Biophysical Chemistry, Göttingen
- 1999 Doctorate (Dr. rer. nat.), Faculty of Mathematics and Natural Sciences, Ruprecht-Karls-University Heidelberg.
- 1995–1999 PhD student, DKFZ Heidelberg
- 1992–1995 Research Associate, Medical Research Center for Hematology RAS, Moscow, Russian Federation.
- 1989–1992 Parental leave
- 1982–1989 Studied biology, Dipl.-Biol., Lomonosov Moscow State University, Russian Federation
Recent publications
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Riesle, A. J., Gao, M., Rosenblatt, M., Hermes, J., Hass, H., Gebhard, A., Veil, M., Grüning, B., Timmer, J., & Onichtchouk, D. (2023). Activator-blocker model of transcriptional regulation by pioneer-like factors. Nature Communications, 14(1), 5677. https://doi.org/10.1038/s41467-023-41507-z
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Baranasic, D., Hörtenhuber, M., Balwierz, P. J., Zehnder, T., Mukarram, A. K., Onichtchouk, D., Daub, C. O., Lenhard, B., & Müller, F. (2022). Multiomic atlas with functional stratification and developmental dynamics of zebrafish cis-regulatory elements. Nature Genetics, 54(7), 1037–1050. https://doi.org/10.1038/s41588-022-01089-w
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Gao, M., Veil, M., Rosenblatt, M., Riesle, A. J., Gebhard, A., Hass, H., Buryanova, L., Yampolsky, L. Y., Grüning, B., Ulianov, S. V., Timmer, J., & Onichtchouk, D. (2022). Pluripotency factors determine gene expression repertoire at zygotic genome activation. Nature Communications, 13(1), 788. https://doi.org/10.1038/s41467-022-28434-1
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Bakhmet, E. I., Nazarov, I. B., Gazizova, A. R., Vorobyeva, N. E., Kuzmin, A. A., Gordeev, M. N., Sinenko, S. A., Aksenov, N. D., Artamonova, T. O., Khodorkovskii, M. A., Alenina, N., Onichtchouk, D., Wu, G., Schöler, H. R., & Tomilin, A. N. (2019). hnRNP-K Targets Open Chromatin in Mouse Embryonic Stem Cells in Concert with Multiple Regulators. Stem Cells, 37(8), 1018–1029. https://doi.org/10.1002/stem.3025
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Iarovaia, O. V., Minina, E. P., Sheval, E. V., Onichtchouk, D., Dokudovskaya, S., Razin, S. V., & Vassetzky, Y. S. (2019). Nucleolus: a central hub for nuclear functions. Trends in Cell Biology, 29(8), 647–659. https://doi.org/10.1016/j.tcb.2019.04.003