Metabolism and signaling of carotenoid degradation products
Biotechnology
CV
Since 2018 group leader, project “InnoBeet – Developing a high-throughput genotype-independent regeneration system for accelerating breeding innovation in sugar beet“, Molecular Plant Physiology, Faculty for Biology, University of Freiburg
2017–2018 Group leader “Nutritional Genomics for Micronutrient-Dense Crops, Phase II” Cell Biology, Faculty for Biology, University of Freiburg
2015 Habilitation in Cell Biology, Faculty for Biology, University of Freiburg
2015–2016 Postdoc, “Nutritional Genomics for Micronutrient-Dense Crops, Phase I“ Cell Biology, Faculty for Biology, University of Freiburg
2011–2014 Principle Investigator, DFG-Fellowship „Carotenoid Steady-State Regulation”, Cell Biology, Faculty for Biology, University of Freiburg
2003–2010 Postdoc “Developing Improved Golden Rice, Faculty for Biology, University of Freiburg
2000–2002 Researcher, Greenovation Plant Technology GmbH and University of Freiburg
1996–2000 PhD in Cell Biology, Faculty for Biology, University of Freiburg
Selected publications
Camagna M, Grundmann A, Bär C, Koschmieder J, Beyer P, Welsch R* (2018) Enzyme fusion removes competition for geranylgeranyl diphosphate in carotenogenesis. Plant Physiol pp.01026.2018
Álvarez D, Voß B, Maass D, Wüst F, Schaub P, Beyer P, Welsch R* (2016) Carotenogenesis Is Regulated by 5′UTR-Mediated Translation of Phytoene Synthase Splice Variants. Plant Physiol 172: 2314–2326
Zhou X, Welsch R*, Yang Y, Álvarez D, Riediger M, Yuan H, Fish T, Liu J, Thannhauser TW, Li L* (2015) Arabidopsis OR proteins are the major posttranscriptional regulators of phytoene synthase in controlling carotenoid biosynthesis. Proc Natl Acad Sci 112: 3558–3563
Arango J, Jourdan M, Geoffriau E, Beyer P, Welsch R* (2014) Carotene Hydroxylase Activity Determines the Levels of Both -Carotene and Total Carotenoids in Orange Carrots. Plant Cell 26: 2223–2233
Welsch R, Arango J, Bar C, Salazar B, Al-Babili S, Beltran J, Chavarriaga P, Ceballos H, Tohme J, Beyer P* (2010) Provitamin A Accumulation in Cassava (Manihot esculenta) Roots Driven by a Single Nucleotide Polymorphism in a Phytoene Synthase Gene. Plant Cell 22: 3348–3356