Selected Publications
- Renner, F., DeRubeis, R., Arntz, A., Peeters, F., Lobbestael, J., & Huibers, M. (2018). Exploring mechanisms of change in schema therapy for chronic depression. Journal of Behavior Therapy and Experimental Psychiatry.
- Renner, F., Ji, J. L., Pictet, A., Holmes, E. A., & Blackwell, S. E. (2017). Effects of Engaging in Repeated Mental Imagery of Future Positive Events on Behavioural Activation in Individuals with Major Depressive Disorder. Cognitive Therapy and Research, 1-12.
- Holmes, E.A., Blackwell, S.E., Burnett Heyes, S., Renner, F., and Raes, F. (2016). Mental imagery in depression: Phenomenology, potential mechanisms, and treatment implications. Annual Review of Clinical Psychology. 12 (1).
- Renner, F., Siep, N., Arntz, A., van de Ven, V., Peeters, F.P.M.L., Quaedflieg, C.W.E.M., Huibers, M.J.H (2017). Negative mood-induction modulates default mode network resting-state functional connectivity in chronic depression. Journal of Affective Disorders. 208, 590-596.
- Renner, F., Arntz, A., Peeters, F. P. M. L., Lobbestael, J., & Huibers, M. J. H. (2016) Schema therapy for chronic depression: Results of a multiple single case series. Journal of Behavioral Therapy and Experimental Psychiatry. 51, 66-73.
FRIAS Project
The (b)link between reward anticipation and depression.
Depression is a major global health problem. Treatment innovation is urgently needed as current treatments are only effective for about half of the patients. A novel, innovative approach to identify treatment targets is to focus on core clinical features rather than the clinical syndrome as a whole. A core clinical feature of depression is reduced reward anticipation: a diminished tendency to expect rewards. A better understanding of the neurofunctional processes underlying this deficit is pivotal for the development of novel treatment innovations. Striatal dopamine (DA) plays a key role in reward processing. Spontaneous eye blink rate (EBR) is a well validated proxy for dopaminergic functioning. The aim of this project is to test the impact of an emotional task targeting reward anticipation on EBR in individuals with depression. My key hypothesis is that spontaneous EBR will modulate the effects of the reward anticipation task. I have developed and validated the reward anticipation task in my previous position at the University of Cambridge. The proposed study will give dynamic insights into the neurofunctional processes underlying reward anticipation and thereby contributes to research on innovative treatment development.