Collaboration

Dr. med. Peter Bronsert

Prof. Dr. med. Dr. Judith Fischer

Link: https://www.uniklinik-freiburg.de/humangenetik/aktuelles.html

Methods: Cloning, Protein expression and purification, Activity measurement

Publications: A Monoallelic Two-Hit Mechanism in PLCD1 Explains the Genetic Pathogenesis of Hereditary Trichilemmal Cyst
Formation. Hörer S, Marrakchi S, Radner FPW, Zolles G, Heinz L, Eichmann TO, Has C, Salavei P, Mahfoudh N, Turki H, Zimmer AD, Fischer J., Invest Dermatol. 2019 Oct;139(10):2154-2163.e5.

Mutations in SULT2B1 Cause Autosomal-Recessive Congenital Ichthyosis in Humans.
Heinz L, Kim GJ, Marrakchi S, Christiansen J, Turki H, Rauschendorf MA, Lathrop M, Hausser I, Zimmer AD, Fischer J., Am J
Hum Genet. 2017 Jun 1;100(6):926-939. doi: 10.1016/j.ajhg.2017.05.007

Prof. Dr. Bodo Grimbacher

Prof. Dr. Andreas Hiltbrunner

Prof. Dr. Carola Hunte

Prof. Dr. Maja Köhn

Link: https://www.bioss.uni-freiburg.de/groups/intergrated-signalling-studies/home/

Methods: Confocal Microscopy

Publication: Dissecting the sequence determinants for dephosphorylation by the catalytic subunits of phosphatases PP1 and
PP2A. Nat Commun. 2020 Jul 17;11(1):3583.

Prof. Dr. Michael Köttgen

Prof. Dr. Thomas Laux

PD Dr. Irina Nazarenko

Dr. Remi Peyronnet

Prof. Dr. Michael Reth

Prof. Dr. Winfried Römer

Dr. Günter Roth

Link: https://biocopy.ch/

Methods: Cloning, Kinetic measurements (Octet RED96 System)

Publication: Comparison of different label-free imaging high-throughput biosensing systems for aptamer binding measurements using thrombin aptamers.
Anal Biochem. 2019 Oct 15;583:113323. doi: 10.1016/j.ab.2019.05.012

Prof. Dr. Oliver Schilling

Link: https://www.uniklinik-freiburg.de/pathologie/forschung/ag-schilling.html

Methods: Cloning, Cell line generation (over-expression / knock-out cell line)

Publication: Impact of DJ-1 and Helix 8 on the Proteome and Degradome of Neuron-Like Cells.
Cells. 2021 Feb 16;10(2):404. doi: 10.3390/cells10020404.

Prof. Dr. Prasad Shastri

Link: http://www.shastrilab.com

Methods: Protein expression and purification, Stable cell line generation (over-expression / knock-out cell line), Cloning

Publication:        Disordered Conformation with Low Pii Helix in Phosphoproteins Orchestrates Biomimetic Apatite Formation.
                                Sarem M, Lüdeke S, Thomann R, Salavei P, Zou Z, Habraken W, Masic A, Shastri VP.
                                Adv Mater. 2017 Sep;29(35). doi: 10.1002/adma.201701629

Dr. Maximilian Ulbrich

Link: http://www.ulbrichlab.com

Methods: Cloning, Kinetic measurement (Octet RED96 System), Polarization measurement, Protein expression and purifica- tion, Stable cell line generation

Publications: Designed membrane protein heterodimers and control of their affinity by binding domain and membrane linker
properties.
Lan C, Stulz A, Barthes N.P.F., Lauw S, Salavei P, Jung M, Heerklotzc H, and Ulbrich M.H.
Nanoscale 2021 Dec 16;13(48):20692-20702, doi: 10.1039/d1nr06574b.

Dr. med Stefan Vestring

Prof. Dr. Wilfried Weber

Link: https://www.bioss.uni-freiburg.de/groups/synthetic-biology/intro/

Methods: Large scale protein expression and purification

Publication: Production of Phytochromes by High-Cell-Density E. coli Fermentation ACS
Synth Biol. 2019 Oct 18;8(10):2442-2450.doi: 10.1021/acssynbio.9b00267.

Collaboration Projects with Research Labs