For detailed information on the equipment available at the Signalhaus and guidance on how to use them effectively, please explore the sections below and refer to our User Guidelines.
The SpectraMax iD5 Multi-Mode Microplate Reader comes with built-in absorbance, fluorescence, luminescence, time-resolved fluorescence (TRF), and tunable fluorescence polarization.
Multi-mode microplate reader the reads a 96-well microplate in 2 min.
The combination of the BioTek EL406 Washer Dispenser, Thermo Scientific RapidSTAK plate stacker, and BioTek Synergy H4 microplate reader creates a powerful automated system for a wide range of liquid handling and analysis applications. This setup enables efficient, high-throughput processing from sample preparation to data acquisition.
The Octet RED96 is a label-free, real-time analysis instrument designed for characterization of protein-protein and protein-small molecule binding kinetics and for determining protein concentrations and titers.
The Zetasizer Nano S90 is a specialized instrument dedicated to the measurement of particle size and molecular weight. It utilizes Dynamic Light Scattering (DLS) technology with a fixed 90° detection angle.
The Seahorse XFe96 Analyzer is a powerful instrument for real-time metabolic analysis of live cells. It offers high-throughput capabilities and versatile applications in cellular metabolism research.
A number of ÄKTA chromatography systems are available for separation and purification of biomolecules at scale ranging from micrograms to grams. The following instruments are located in the Signalhaus:
Our ÄKTA systems are equipped with a broad range of chromatographic columns and media, which cover all main types of chromatographic techniques: size exclusion, cation and anion exchange, affinity, hydrophobic interaction and immobilized-metal affinity (IMAC) chromatography.
This ultra HPLC machine is a reliable system designed to provide fast analytical separations with highest sensitivity and highest resolution.
The modules available in our laboratory include:
The Attune NxT Flow Cytometer is an advanced, high throughput, benchtop cytometer that uses acoustic pressure to confine the injected particles to a tight central line as the sample passes through the optical cell for interrogation.
The CyAn ADP High-Performance Flow Cytometer is a research tool engineered for precision analysis of cells, bacteria, and other similarly sized particles.
The S3 Cell Sorter is an automated benchtop cell sorter that provides exceptional sort purity, recovery, and yield without compromising performance and sensitivity.
For detailed information about our service please refer to our Cell Sorting Service.
The CyFlow® Cube is a compact flow cytometer for analysis of single cells and microscopic particles.
Optimized luminescence and fluorescence imaging system for quantitative image acquisition.
Laser-based imager for excitation of near-infrared (NIR) fluorescence dyes.
Nucleofector® II device is a tool for highly efficient non-viral transfection of primary cells and difficult-to-transfect cell lines
Gene Pulser MXcell systems can be used to electroporate as few as 105 cells by using a 96-well plate or as many as 106 to 107 cells in a 12-well plate or in a cuvette.
The Multiporator can be used for electroporation of animal and human cells, primary cells, plant cells and embryonic stem cells. The system provides multiple pulsing from 1 to 99 pulses with a one-minute interval.
For transformation of bacteria, yeast, and other microorganism. Manual programming allows voltage to be selected in a 200–3,000 V range with 10 V precision and allows pulse width to be selected in a 1.0–4.0 ms range with 0.1 ms precision
Our robotics facility offers an automation for High Throughput Screening (HTS) protocols as well as iterative process for applied research.
An HTS work involved a step by step development from an early design of experiment, optimization to the transfer for automation.
Read our User Guidelines for detailed information about instrument usage and services.
Through the development and optimization, we can assure the screening to have a good quality of result, low cost and optimum time.
The Robotics Facility offers the infrastructure and expertise to support research groups of the University of Freiburg and the University Medical Center Freiburg.
We collaborate with research groups providing project support in handling extensive numbers or iterative process of handling liquid and suspension to accommodate scientific works. We also offer collaborations for individual method and assay development.
A selection of research laboratories who collaborate with us in long-term projects are listed at our collaborators.